Developments of Tsunami Observing Systems in Japan

Being situated on the major subduction zones in conjunction with a considerable number of submarine active faults and coastal volcanoes, Japan has a LEGO Model long history of catastrophic tsunami events.Consequently, enormous efforts in disaster mitigation, particularly in relation with tsunami hazards, have been made across the country.It is of o

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Laparoscopic Pelvic Floor Repair Using Polypropylene Mesh

Objective: The purpose of this report is to present our experience in laparoscopic pelvic floor repair using polypropylene mesh for the treatment of advanced vaginal vault prolapse and enterocele.Materials and Methods: A total of 40 Acavallo Gel patients with Baden-Walker System grade 3 or 4 vaginal vault prolapse and concurrent enterocele were rec

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Insight on ecDNA-mediated tumorigenesis and drug resistance

Extrachromosomal DNAs (ecDNAs) are a pervasive feature found in cancer and contain oncogenes Metal Halide and their corresponding regulatory elements.Their unique structural properties allow a rapid amplification of oncogenes and alter chromatin accessibility, leading to tumorigenesis and malignant development.The uneven segregation of ecDNA during

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